If you've worked with AFFF firefighting foam, or you live somewhere with PFAS in the water, there's a good chance your levels are high even if you've never been tested. Grain Laboratories is enrolling fifteen adults with elevated serum PFOS for a twelve-week NeutraOat pilot. You'll get two PFAS panels and two wellness panels, one set before dosing and one after. You keep your own results, and the combined results tell us whether NeutraOat is worth a larger study.
NeutraOat is a modified form of oat fiber (β-glucan) that binds PFAS in your gut before they get reabsorbed. It's food-grade and made from oats. The idea is to grab the compounds you don't want in your body while mostly leaving alone the nutrients and medications you do.
PFAS molecules have a long, greasy tail. We add microscopic water-repelling pockets to oat fiber through an enzyme step, and those pockets are shaped to fit that tail. Most of the things your body needs are the wrong shape to fit, so they pass on through.
PFAS sticks around because the liver dumps it into bile, and then the gut reabsorbs it. The same molecules get recycled this way for years. If something binds the PFAS while it's in the gut, that loop is broken and the PFAS leaves the body.
A published 2024 trial used cholestyramine, a prescription bile-acid binder that works the same way in the gut, and saw about a 60% drop in PFOS over 12 weeks at 12 g a day. The catch with cholestyramine is that it binds almost everything, and a lot of people can't tolerate it. NeutraOat goes after the same mechanism at 4 g a day and is built to be choosier about what it grabs. This pilot is the first time we're testing it in people.
Almost everyone has some PFAS in their blood, but two kinds of exposure tend to push levels much higher: direct contact with AFFF firefighting foam, and living somewhere with known PFAS contamination. You don't need a recent blood test to apply. If your exposure history is clear, we'll cover the baseline panel that confirms your levels. We're prioritizing firefighters and others exposed to AFFF, and keeping spots open for people from contaminated communities.
Everything happens at home. No clinic visits, no travel, and nothing runs through insurance.
Two at-home kits arrive at your door. The first is a finger-prick PFAS panel from Relentless Health, measuring PFOS, PFOA, and PFHxS. The second is a comprehensive wellness panel covering thyroid, hormones, metabolic, lipid, inflammation, and nutrient markers across 40+ biomarkers. Both ship back the same day. You receive your full baseline results before dosing begins.
Four grams per day of NeutraOat, taken as two grams twice daily, pre-meal. We ship enough for the full duration.
A five-minute online diary covering how you're tolerating it, whether you're staying on schedule, and any GI symptoms. If anything looks concerning, it goes straight to Grain Labs and, when it makes sense, to your doctor.
The same two kits go out again, followed by a thirty-minute conversation about how it went, what worked and what didn't, and what you'd be willing to pay for it. You'll see how your numbers changed against your own baseline. There's an optional follow-up sample at week sixteen that shows what happens to your levels after you stop.
There are no copays, deductibles, or out-of-pocket costs. Grain Laboratories covers twelve weeks of NeutraOat, two PFAS panels, and two wellness panels. All we ask from you is the time.
Food-grade NeutraOat, batch-tested, shipped to you.
Baseline and week-12 finger pricks via Relentless Health. PFOS, PFOA, and PFHxS, run at the same lab with the same method, directly comparable.
40+ biomarkers at baseline and week 12, covering thyroid, hormones, metabolic, lipid, inflammation, and nutrient markers.
Grain Laboratories is the Boston-based company developing NeutraOat. We design the protocol, supply the product, run participant communications, and analyze the results. Our research partner at the University of Alberta produces the pilot batch.
Relentless Health handles PFAS testing. The same paired methodology and instrument are used at baseline and week 12, so your before-and-after numbers are directly comparable.
Trevor Klee, Founder & CSO, Grain Laboratories
Reach us via the NeutraOat contact form →
Available throughout the program. If you report a side effect, it goes to Grain Labs and, when appropriate, your primary care doctor.
If something here doesn't answer what you're wondering, get in touch.
A modified oat-fiber product designed to capture PFAS in the gut before it gets reabsorbed. Food-grade, taken twice daily for twelve weeks.
Oatmeal might help a little, but not much. We start from a purified oat fiber called β-glucan and run it through an enzyme step that adds water-repelling pockets shaped to fit PFAS molecules. Plain oatmeal doesn't have any of that.
NeutraOat is not certified organic. Glyphosate residue is a fair question for any oat-derived product, and we've thought carefully about it.
The starting material for NeutraOat is purified oat β-glucan, not whole oats or oat flour. Two factors make residue carryover unlikely:
The pilot batch has not yet been tested for glyphosate, AMPA, or a broad pesticide panel. The starting β-glucan has been tested by our supplier for heavy metals, microbial contamination, and gluten. The certificate of analysis is available on request. Pesticide panel testing (including glyphosate-specific LC-MS/MS) will be part of the release specification for commercial batches, and those results will be published.
No. NeutraOat is a non-prescription product, not FDA-approved as a treatment. This pilot is the first human study of it.
We think it will, but we're not certain. That's what the pilot is meant to find out. The reason we're optimistic: cholestyramine, a prescription bile-acid binder that works the same way in the gut, lowered PFOS by about 60% in a published 2024 trial. NeutraOat is built to do the same job in food-grade form, at a lower dose, and to be more selective about what it binds.
NeutraOat is modified oat fiber. It moves through the digestive tract in about three hours, isn't absorbed into the bloodstream, and leaves the body intact. The most likely side effects are the same as with any fiber: mild GI effects like gas or bloating. The protocol has been reviewed by independent clinicians, and an independent clinician advises the program throughout.
Most medications are fine. GLP-1 agonists, like Mounjaro or Ozempic, are fine. So are over-the-counter medications, like Advil or Tylenol.
The only medications that aren't fine are ones where small dose changes can be dangerous clinically. The following disqualify you from participation:
If you take something not on this list and you're unsure, apply anyways. The application form screens for medications and conditions that would interact with the product.
Yes. We're pretty sure NeutraOat won't interfere with your meds or supplements, but we'd rather be safe than sorry.
Take NeutraOat 1 to 2 hours apart from any medications, prescription or over-the-counter, and from any vitamins or supplements. This is the same dose-separation practice that's standard with prescription bile-acid binders like cholestyramine.
NeutraOat is taken twice a day before meals, so for most people the easiest routine is to move other pills to a different part of the day. We'll walk through your schedule on the intake call.
No. Your individual results go to you. Nothing is shared with your employer, your department, or any third party without your explicit written consent.
Yes. You'll see your baseline PFAS panel and wellness panel before dosing starts, and your week-12 results when they return. Both sets are yours to keep, and we'll walk you through what the numbers mean if you'd like.
No. We're not selling or sharing your information, and we won't add you to a marketing list. The data is collected for the pilot. That's it.
Participation is independent of any litigation. We don't share participant information with attorneys, employers, or any third party. If you have active legal questions, check with your lawyer before applying.
Yes. If you've had direct contact with AFFF firefighting foam, or you live in a community with documented PFAS contamination, apply. A prior test isn't required.
We cover a baseline PFAS panel through Relentless Health at intake. A result at or above 4 ng/mL confirms your spot, and that same panel becomes your study baseline.
There's a good chance if your public water system has reported PFAS above EPA limits, or you live near a military base or airfield, a fire-training site, or a fluorochemical or manufacturing plant.
You don't have to work this out on your own. Apply, tell us what you know about your water and your location, and the baseline test settles it.
Apply anyway. If you'd otherwise qualify, we'll cover a new PFAS panel through Relentless Health as part of intake. That becomes your baseline.
Same rules apply: an adult with either elevated PFOS or a strong AFFF / PFAS-community exposure history, no active GI conditions, and no current bile-acid binder use. If that's them, send them to apply.
We want you to know exactly what you're signing up for. This is a discovery cohort: a small, structured study meant to gather early signal and tolerability data before a larger trial. We'd rather be upfront about what it can and can't tell us.
The screener checks eligibility, asks about commitment and any GI conditions, and collects your contact details. If you qualify, you'll be invited to book a fifteen-minute intake call to walk through consent and finalize enrollment.